{"id":147,"date":"2010-01-08T07:04:38","date_gmt":"2010-01-07T23:04:38","guid":{"rendered":"http:\/\/www.naturalpathremedies.com\/blog\/?p=147"},"modified":"2026-05-27T22:02:46","modified_gmt":"2026-05-28T05:02:46","slug":"paw-paw-program","status":"publish","type":"post","link":"https:\/\/www.NaturalPathRemedies.com\/blog\/paw-paw-program\/","title":{"rendered":"Paw Paw Program &#8211; How It Works"},"content":{"rendered":"<p><strong><a title=\"Paw Paw\" href=\"https:\/\/www.naturessunshine.com\/product\/paw-paw?referrer=1143615\" target=\"_blank\" rel=\"noopener\">Paw Paw<\/a><\/strong> is an herb that is part of\u00a0 a natural program for cancer treatment. The correct species of this herb which has more than 30 years research, is\u00a0 <em><strong>Asimina trilob<\/strong><strong>a<\/strong><\/em>, which is native to the eastern U.S. Over fifty bio-active components of Paw Paw have been discovered in this particular species, specifically made from the tree twigs of a certain age. The major active compounds, which have been found effective in this cancer research, are called the annonaceous acetogenins. These have been described in a series of research papers as representing the most potent, major, bio-active structural types of acetogenins. These are only found in the standardized <strong><a title=\"Paw Paw\" href=\"https:\/\/www.naturessunshine.com\/product\/paw-paw?referrer=1143615\" target=\"_blank\" rel=\"noopener\">Paw Paw<\/a><\/strong> concentrate available from <a href=\"http:\/\/takethenaturalpath.mynsp.com\/\" target=\"_blank\" rel=\"noopener\">Nature\u2019s Sunshine.<\/a> The critical difference is in the quantity and quality of the active ingredient or acetogenins, found in this species.<\/p>\n<p>The research from Purdue University by Dr. Jerry McLaughlin&#8217;s group, as well as Wayne State University, has shown that Paw Paw works as a chemotherapeutic agent, with <strong>no side effects<\/strong>.\u00a0 It has been shown to work via four specific mechanisms:<\/p>\n<p>1)\u00a0\u00a0 \u00a0The acetogenins in Paw Paw <strong>modulate the production of ATP in the mitochondria of abnormal cells<\/strong>. All cells require energy to reproduce, but cancer cells are programmed to replicate at up to 17 times the rate of normal cell reproduction. Because acetogenins modulate the production of ATP, cancer and other abnormally growing cells do not thrive, while healthy, normally reproducing cells are unaffected. More technically, the acetogenins are potently cytotoxic and inhibit complex I in the electron transport system in mitochondria; the effect being depletion of ATP levels and induced apoptosis. They also inhibit the NADH oxidase found in the plasma membranes of tumour cells. This selective targeting affects the viability of abnormal cells will enhance the overall health of the body.<\/p>\n<p>2)\u00a0\u00a0 \u00a0<strong>Paw Paw helps inhibit the growth of blood vessels<\/strong> that nourish cancer cells. This process is called anti-angiogenesis.<\/p>\n<p>3)\u00a0\u00a0 \u00a0<strong>Paw Paw depletes the DNA and RNA building blocks necessary for new cell division<\/strong>.\u00a0 Although Paw Paw exhibits this action on abnormally growing cells, it has also been shown, in a recent clinical study with over 100 participants, that it supports the body\u2019s normal cells. Studies with cell cultures of normal versus cancerous cells showed early on that the acetogenins are relatively less toxic to normal cells; indeed, certain acetogenins are often selectively cytotoxic toward one or only a few cancer cell lines. This means that whereas many cytotoxic drugs used cause cachexia, (weight loss), and energy loss, Paw Paw has shown opposite results.<\/p>\n<p>4)\u00a0\u00a0 \u00a0The <strong>acetogenins are especially effective against multi drug resistant tumours (MDR), which can become resistant to the chemotherapy drugs.<\/strong> Paw Paw limits the ATP &#8211; dependant efflux pump (glycoproteins) function. Therefore Paw Paw can be toxic even to cancer cells that are drug resistant.<\/p>\n<p><strong>Paw Paw<\/strong> is a valuable tool in strengthening and supporting the immune system. Even if one chooses to use chemotherapy treatment, Paw Paw can actually enhance the effects of chemotherapy, as acetogenins are especially effective against multi-drug resistant (MDR) tumours, as per #4 above. (Please check out chemotherapy statistics and side effects before you make this decision.)<\/p>\n<p>Previous clinical studies of the acetogenins in cancer patients have been thwarted due to their unavailability in pure form. Other related species such as graviola, guanabana, and Brazilian paw paw contain only the less potent monotetrahydrofuran acetogenins, and do not maximize acetogenin levels or standardize the product to assure consistent potency.<\/p>\n<p><strong>Paw Paw<\/strong> works in conjunction with enzymes, correct balance of essential fatty acids, minerals, immune enhancers, such as Silver Shield, Zambroza, Astragalus, and dietary, emotional and other lifestyle recommendations to ensure a holistic approach. For a more detailed scientific explanation, research, or case histories, contact <a href=\"http:\/\/naturalpathremedies.com\/contact\/\" target=\"_blank\" rel=\"noopener\">Benoit &amp; Associates Health Education<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Paw Paw is an herb that is part of\u00a0 a natural program for cancer treatment. The correct species of this herb which has more than 30 years research, is\u00a0 Asimina triloba, which is native to the eastern U.S. Over fifty bio-active components of Paw Paw have been discovered in this particular species, specifically made from &hellip; <a href=\"https:\/\/www.NaturalPathRemedies.com\/blog\/paw-paw-program\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Paw Paw Program &#8211; How It Works<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30,22],"tags":[994,51],"class_list":["post-147","post","type-post","status-publish","format-standard","hentry","category-cancer","category-healthy-solutions","tag-cancer","tag-paw-paw"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Paw Paw Program - How It Works - Natural Path Remedies Research Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.NaturalPathRemedies.com\/blog\/paw-paw-program\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Paw Paw Program - How It Works - Natural Path Remedies Research Blog\" \/>\n<meta property=\"og:description\" content=\"Paw Paw is an herb that is part of\u00a0 a natural program for cancer treatment. The correct species of this herb which has more than 30 years research, is\u00a0 Asimina triloba, which is native to the eastern U.S. Over fifty bio-active components of Paw Paw have been discovered in this particular species, specifically made from &hellip; Continue reading Paw Paw Program &#8211; How It Works &rarr;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.NaturalPathRemedies.com\/blog\/paw-paw-program\/\" \/>\n<meta property=\"og:site_name\" content=\"Natural Path Remedies Research Blog\" \/>\n<meta property=\"article:published_time\" content=\"2010-01-07T23:04:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-28T05:02:46+00:00\" \/>\n<meta name=\"author\" content=\"LoreneB\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"LoreneB\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/\"},\"author\":{\"name\":\"LoreneB\",\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/#\\\/schema\\\/person\\\/922cfcaeab796586cb230ebce7cbd2f5\"},\"headline\":\"Paw Paw Program &#8211; How It Works\",\"datePublished\":\"2010-01-07T23:04:38+00:00\",\"dateModified\":\"2026-05-28T05:02:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/\"},\"wordCount\":628,\"commentCount\":4,\"keywords\":[\"Cancer\",\"Paw Paw\"],\"articleSection\":[\"Cancer\",\"Healthy Solutions\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/\",\"url\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/\",\"name\":\"Paw Paw Program - How It Works - Natural Path Remedies Research Blog\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/#website\"},\"datePublished\":\"2010-01-07T23:04:38+00:00\",\"dateModified\":\"2026-05-28T05:02:46+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/#\\\/schema\\\/person\\\/922cfcaeab796586cb230ebce7cbd2f5\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/paw-paw-program\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Paw Paw Program &#8211; How It Works\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/\",\"name\":\"Natural Path Remedies Research Blog\",\"description\":\"Take the natural path\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.NaturalPathRemedies.com\\\/blog\\\/#\\\/schema\\\/person\\\/922cfcaeab796586cb230ebce7cbd2f5\",\"name\":\"LoreneB\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/23882ccc18dc9edd4c9a5d507027aabf1e117f1496f460ab541a44c4cb58c8ca?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/23882ccc18dc9edd4c9a5d507027aabf1e117f1496f460ab541a44c4cb58c8ca?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/23882ccc18dc9edd4c9a5d507027aabf1e117f1496f460ab541a44c4cb58c8ca?s=96&d=mm&r=g\",\"caption\":\"LoreneB\"},\"description\":\"Lorene Benoit is a Natural Health Consultant and Educator. 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