Q & A Graviola, Papaya versus Paw Paw – Asimina triloba

UPDATE: Mar, 2021:  at end of article

 

Questions:

Is Sour Sop, Guanabana or Brazilian Graviola the same as in your Paw Paw Program book?  Anita R.

Is Paw Paw the same thing as Papaya Leaf?  Dan

Answer:

NO.

Both the sour sop juice and papaya leaf are totally different species of the plant and totally different preparations from the Paw Paw, Latin name Asimina triloba that has been researched as effective for cancer. Although there is some correct information on the site you mentioned, there is also some misinformation, especially concerning the research reference.(see end of this article).

In the field of medicinal herbals, it is paramount to understand which species of a plant one is using. Many plants have the same family name, but chemical composition within a species, and within different parts of the plant, varies widely. The same name may also apply to completely different plants in different parts of the world. For example, many countries have different plants they call Heal All, which are not even in the same plant family. Latin names, or nomenclature, are the only way to scientifically identify, and reproduce the medicinal benefits.

For accuracy,  always use the Latin name of the plant, which in the case my book, The Paw Program – A “Christopher Columbus” Approach to Cancer, refers to the Paw Paw tree, Asimina triloba, standardized twig bark,  harvested at the correct time. This plant is native to the eastern U.S.

Please contact us to get the correct source, direct discount pricing, AND support from an expert.

From page 90 – 91 of Lorene Benoit’s  book: ” Paw Paw is one of the most researched and most effective herbal remedies in connection with cancer. In the past 30 years research on Paw Paw has been conducted by Dr. Jerry McLaughlin and a team of researchers at Purdue University, as well as at Wayne State University.”

Over fifty bioactive compounds, called the annonaceous acetogenins, have been found in the standardized Paw Paw concentrate of this particular species of Paw Paw. These have been described in a series of research papers as representing the most potent, major, bioactive structural types of acetogenins.

Other related species of Annona muricata, also known as graviola, guanabana, Sour sop, and Brazilian Paw Paw contain only the less potent monotetrahydrofuran acetogenins, and do not maximize acetogenin levels or standardize the product to assure consistent potency.
Beware when checking sources online, that you will not only receive the correct herb, but that you have someone to contact for ongoing support. 

In addition, the health of the tree,  part used,  time of year that the twig is harvested for optimum potency, and how it is processed,  and tested, ALL effect the outcome.

To ensure you get the correct herbal preparation that has been researched, the best price, plus support, please contact the author.

As part of Dr. McLaughlin’s research, one study of 100+ patients, with many types of tumours represented,  resulted in:

Significant reductions seen in tumor sizes (verified by CT, etc.)

Significant reductions in tumor antigen levels (PSA, CA2729, CA125, alkaline phosphatase, etc.)

Very few side effects; mostly none; nausea and vomiting (2 people); itching (1 person); many reported “increased energy”

No hair loss, no bone marrow depression, No GI bleeding

Benefits were also seen with cold sores, shingles, MS, toe nail fungus, acne, athletes foot, eczema & psoriasis (in capsules, lotion and salve formulations).

These results were with the standardized extract of Paw Paw as prepared, tested & supervised by Dr. Jerry McLaughln, and encapsulated by Nature’s Sunshine Products. To order, please contact our office. You can also receive professional advice from the author, which is not available when ordering from Amazon.

Case studies conducted by Dr. Forsythe, a Nevada oncologist are included in my book, including complete remissions with stage four cancers as well as Testimonials offered  from my own clients.

I have included excerpts from pages 6-8 of a 37 page report from the Journal Natural Products, 1999, 62 504-540, titled: Annonaceous Acetogenins: Recent Progress

by Feras Q. Alali, Xiao-Xi Liu, and Jerry L. McLaughlin*, Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907

Should you wish the whole technical report with all 138 References included,  search online, or contact our office, with this in subject line: Acetogenins Tech Review JNP 1999

The Annonaceae (custard-apple family), is very large, 130 genera and 2300 species. Phytochemical studies and, to a lesser extent, pharmacological studies on Annonaceous species have intensified in the last 15 years; this is largely due to the discovery of the Annonaceous acetogenins, a class of natural compounds with a wide variety of biological activities.

The discovery of uvaricin in 1982,7 the first of the Annonaceous acetogenins,
as an in vivo active antileukemic (P-388) agent, invigorated wide interest in this family. The Annonaceous acetogenins are now one of the most rapidly growing classes of new natural products and offer exciting anthelmintic,(kills worms),  in vivo and cytotoxic antitumor, antimalarial, antimicrobial, antiprotozoal, and pesticidal activities and special promise of becoming new chemotypes for antitumor and pesticidalagents.

Note: American pawpaw (Asimina triloba) is not a papaya and should not be confused with Carica papaya or Annona muricata (graviola) although the species have similar common names and may be called “pawpaw.”

I agree with what the website you sent me cited, concerning why the public has not heard as much about the Paw Paw family for an effective cancer approach.

However, this site mentions tests at Purdue University showed results with graviola leaves. This is not true; graviola  (Annona muriatica) did not show the effectiveness that Paw Paw  Cell Reg (Asimina triloba) twig bark extract did, because they do not contain the acetogenin varieties or strength.

http://inspireurfriend.blogspot.in/2012/10/10000-times-stronger-killer-of-cancer.html

“….under federal law, a natural product is not patentable. There’s no way to make serious profits from it. There was no way the company could protect its profits–or even make back the millions it poured into research. As the dream of huge profits evaporated, their testing on Graviola came to a screeching halt.”

This is, unfortunately in our big pharma profit driven market of disease care, the truth for all natural and herbal products.

 

UPDATE: Mar, 2021:

Be suspicious of sites such as Wikipedia that usually negate health benefits of any natural medicines. They are supported by global pharma interests.

Two examples:

  • I just picked some Guanabana fruit in Mexico and wanted to do a bit of research on it. This is one species of the Annoncea family, Annona muricata.  Wikipedia said it was neurotoxic and of no benefit at all for cancer, beware of charlatan claims, blah, blah…..  almost no  references to support their claim.The first scientific review I looked up presented quite a different story, including research proving no neuro-toxic effects,  in any ‘normal quantity’, with results from multiple studies. It references well  more than 100 scientific research articles. https://www.frontiersin.org/articles/10.3389/fphar.2018.00661/full
  • I then looked up Asimina triloba on Wikipedia. This is the Paw Paw that we have used as a natural chemotherapy since the extract became approved in 2003. Not one mention of medicinal benefits, although it has been used successfully since 2003. And there are hundreds, if not thousands, of references, including the 30 years of published research by Dr. Jerry McLaughlin.  A few excerpts from the first review I opened by Science Direct:

… two additional acetogenins, muricoreacin and murihexocin, showed significant cytotoxicities in six human tumor cells, including PACA-2 pancreatic carcinoma and PC-3 prostate adenocarcinoma cell lines [142].

Two annonaceous species, A. muricata and Asimina triloba (‘paw paw’),  both yield acetogenins.  Annonaceous acetogenins, bullatacin, showed 300 times the potency of taxol against L1210 murine leukemia [143,144]. Bullatacin and several other acetogenins do so by inhibiting adenosine triphosphate (ATP) production. This has profound implications for the development of complex acetogenin drugs that could be very effective against multidrug-resistant tumors [145]. https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/asimina-triloba

 

7 thoughts on “Q & A Graviola, Papaya versus Paw Paw – Asimina triloba

  1. I have to thank you for the efforts you’ve put in penning this website. I am hoping to check out the same high-grade blog posts from you later on as well.

  2. This is a good posting, I was wondering if I could use this write-up on my website, I will link it back to your website. If this is a problem please let me know and I will take it down right away.

  3. It is the bark of the twig harvested when the acetogenins test at their peak, just about this time of this year. This is the only tested and standardized Paw Paw that we have used successfully. The dried bark is standardized to contain 17 mg. acentogenins per 2 capsules.Please get back in touch if you are in US or CA and would like to order any at discount.Or for fast service, just call our office: 250-748-6802.
    We believe in personal service.

  4. My name is Ron my wife has stage 4 kidney cancer and went through 2 treatments of immunotherapy and then had severe side effects. She has since then started taking paw paw can you tell me if this is a possible benefit to her.

  5. Thank you for your contact, sorry for what you & your wife are dealing with. It affects everyone.
    Using a natural, proven chemo-therapeutic such as Asimina triloba standardized extract can do NO HARM, if used properly. This is supposed to be a basic tenet of all “medicine”. Unfortunately it sounds like the immunotherapy did not meet this criteria.
    As to how much benefit this will provide, without knowing more about your wife, her source of Paw Paw, her lifestyle, full natural program, her state of mind and belief system, it would be unprofessional of me to comment. Please contact me directly if you would like more specific support. A phone number would be best as with stage 4, you want to get her on track fast.

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